Genetic Predisposition and Dietary Shifts Elevate Fatty Liver Disease Risk Among Indian Populations, Warns Senior Cardiologist

A distinguished cardiologist with four decades of clinical experience has issued a critical health intelligence alert regarding the escalating prevalence of non-alcoholic fatty liver disease (NAFLD) within Indian demographics. Dr. Chopra's analysis identifies a potent confluence of historical genetic adaptations and contemporary lifestyle factors as the primary drivers of this public health concern. He posits that evolutionary adaptations developed to survive historical periods of famine have rendered certain populations, including many in India, metabolically predisposed to storing fat in the liver under modern conditions of caloric abundance and sedentary behavior. This genetic susceptibility, when combined with rapid dietary transitions towards processed foods and high sugar intake, creates a perfect storm for hepatic steatosis. The report underscores that this condition is no longer a benign finding but a significant precursor to cirrhosis, cardiovascular events, and metabolic syndrome. To counter this trajectory, Dr. Chopra advocates for a strategic, evidence-based intervention protocol centered on sustained lifestyle modification. Key protective measures include the adoption of a whole-foods, plant-leaning diet low in refined carbohydrates and fructose; the implementation of regular, moderate-intensity physical activity; and proactive weight management. This analytical assessment concludes that mitigating this risk requires a paradigm shift from reactive treatment to proactive, population-wide preventive health strategies informed by this genetic and metabolic understanding.